Nox2-dependent neuroinflammation in an EAE model of multiple sclerosis
نویسندگان
چکیده
منابع مشابه
P 153: Neuroinflammation in Multiple Sclerosis
Multiple sclerosis (MS) is a complex disease which is correlated with increasing inflammatory factors, demyelination and axonal loss. In this auto-immune disease, Neuroinflammation is mediated by different types of T cells with macrophage/microglial activation and B cells involvement that interact in a collaborative manner. Focal inflammation is the main cause for the onset of relapses and coul...
متن کاملP121: The Effect of Stress on Neuroinflammation in Multiple Sclerosis
Multiple sclerosis (MS) is a chronic autoimmune disorder of central nervous system. This demyelinating disease affects more than 2.3 million people world wild. Most of patients are young adult. There are many possible triggering factors including infections, toxin, immunization, trauma, sunlight exposure and hormonal variable in pathogenesis of MS. One of the important trigger is stress. There ...
متن کاملP174: Expression of Cannabinoid Receptor 1 (CB1) in Animal Model of Multiple Sclerosis (EAE) Treated with Hemp Seed Oil
Multiple sclerosis (MS), as an auto-immune disease, is confined to the central nervous system and is usually accompanied with debilitating condition in MS patient. The rate of disease in the females is more than males (2:1), and it is diagnosed between 20 to 40 years old. Phototherapy, as a traditional remedy, is used to treat different pathological conditions including MS. Hemp seed oil, as an...
متن کاملcost benefits of rehabilitation after acute coronary syndrome in iran; using an epidemiological model
چکیده ندارد.
B cell antigen presentation is sufficient to drive neuroinflammation in an animal model of multiple sclerosis.
B cells are increasingly regarded as integral to the pathogenesis of multiple sclerosis, in part as a result of the success of B cell-depletion therapy. Multiple B cell-dependent mechanisms contributing to inflammatory demyelination of the CNS have been explored using experimental autoimmune encephalomyelitis (EAE), a CD4 T cell-dependent animal model for multiple sclerosis. Although B cell Ag ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Translational Neuroscience
سال: 2019
ISSN: 2081-6936
DOI: 10.1515/tnsci-2019-0001